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1

GTP Analogue Inhibits Polymerization and GTPase Activity of the Bacterial Protein FtsZ without Affecting Its Eukaryotic Homologue Tubulin †

Läppchen, Tilman, Hartog, Aloysius F., Pinas, Victorine A., Koomen, Gerrit-Jan, den Blaauwen, Tanneke

Journal:

Year:

2005

Language:

english

File:

PDF, 253 KB

english, 2005

2

Synthesis of the Cyclostellettamines A−F and Related Bis(3-alkylpyridinium) Macrocycles

Martin J. Wanner, Gerrit-Jan Koomen

Journal:

European Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 477 KB

english, 1998

3

ChemInform Abstract: Purine Nucleoside Analogues. Part 9. Benzylation of N2-Acetyl-8-bromoguanine.

Marina Madre, Natella Panchenko, Regina Zhuk, Jan A. Geenevasen, Alida van den Burg, Gerrit-Jan Koomen

Journal:

Year:

1999

File:

PDF, 25 KB

1999

4

ChemInform Abstract: Purine Nucleoside Analogues. Part 11. An Alternative Synthesis of N- and O-Alkyl Derivatives of 9- and 7-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine.

Marina Madre, Natella Panchenko, Alexander Golbraikh, Regina Zhuk, Upendra K. Pandit, Jan Geenevasen, Gerrit-Jan Koomen

Journal:

Year:

1999

File:

PDF, 34 KB

1999

5

ChemInform Abstract: Palladium-Catalyzed Amination of 6-Chloropurine. Synthesis of N6-Substituted Adenosine Analogues.

Judith Barends, Johannes B. van der Linden, Floris L. van Delft, Gerrit-Jan Koomen

Journal:

Year:

2000

File:

PDF, 31 KB

2000

6

ChemInform Abstract: Regioselective Nitration of Purine Nucleosides: Synthesis of 2-Nitroadenosine and 2-Nitroinosine.

Paymaneh Y. F. Deghati, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

2000

File:

PDF, 28 KB

2000

7

ChemInform Abstract: Enantiopure Tetrahydro-β-carbolines via Pictet—Spengler Reactions with N-Sulfinyl Tryptamines.

Christiaan Gremmen, Bianca Willemse, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

2000

File:

PDF, 30 KB

2000

8

ChemInform Abstract: 2-Nitro Analogues of Adenosine and 1-Deazaadenosine: Synthesis and Binding Studies at the Adenosine A1, A2A, and A3 Receptor Subtypes.

Martin J. Wanner, Jacobien K. Von Frijtag Drabbe Kuenzel, Ad P. IJzerman, Gerrit-Jan Koomen

Journal:

Year:

2000

Language:

english

File:

PDF, 40 KB

english, 2000

9

ChemInform Abstract: Synthesis of New Bridged Tetrahydro-β-carbolines and spiro-Fused Quinuclidines.

Brigitte E. A. Burm, Christiaan Gremmen, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

2001

Language:

english

File:

PDF, 39 KB

english, 2001

10

ChemInform Abstract: Synthesis of Xestomanzamines A and B.

Brigitte E. A. Burm, Peter Blokker, Edwin Jongmans, Erwin van Kampen, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

2001

File:

PDF, 33 KB

2001

11

ChemInform Abstract: Synthesis and Properties of 2-Nitrosoadenosine.

Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

2002

File:

PDF, 34 KB

2002

12

ChemInform Abstract: Enantiopure Tetrahydroisoquinolines via N-Sulfinyl Pictet—Spengler Reactions.

Christiaan Gremmen, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

2002

File:

PDF, 30 KB

2002

13

A New Synthesis of Temozolomide.

Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

2003

File:

PDF, 122 KB

2003

14

Enzyme catalysed oxidation of nazlinin and nazlinin derivatives. Characterisation of the reaction products

Elisabeth Cheng, Jens Botzem, Martin J. Wanner, Brigitte E.A. Burm, Gerrit-Jan Koomen

Journal:

Year:

1996

Language:

english

File:

PDF, 464 KB

english, 1996

15

Sythesis of novel annulated ellipticines via Claisen rearrangement reactions

Johannes P.M. Plug, Gerrit-Jan Koomen, Upendra K. Pandit

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 254 KB

english, 1992

16

Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5′-carboxamidoadenosine analogues

Boris Rodenko, Remko J. Detz, Victorine A. Pinas, Catia Lambertucci, Reto Brun, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

17

Probing FtsZ and Tubulin with C8-Substituted GTP Analogs Reveals Differences in Their Nucleotide Binding Sites

Tilman Läppchen, Victorine A. Pinas, Aloysius F. Hartog, Gerrit-Jan Koomen, Claudia Schaffner-Barbero, José Manuel Andreu, Daniel Trambaiolo, Jan Löwe, Aurélie Juhem, Andrei V. Popov, Tanneke den Blaa

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 1.14 MB

english, 2008

18

Synthesis of new bridged tetrahydro-β-carbolines and spiro-fused quinuclidines

Brigitte E.A Burm, Christiaan Gremmen, Martin J Wanner, Gerrit-Jan Koomen

Journal:

Year:

2001

Language:

english

File:

PDF, 172 KB

english, 2001

19

Regiospecific C-9 substitution of ellipticine derivatives

Albert Langendoen, Johannes P.M. Plug, Gerrit-Jan Koomen, Upendra K. Pandit

Journal:

Year:

1989

Language:

english

File:

PDF, 350 KB

english, 1989

20

Synthesis of ring C modified sesbanimide analogues

Wilhelmus J. Vloon, Jan C. van den Bos, Gerrit-Jan Koomen, Upendra K. Pandit

Journal:

Year:

1992

Language:

english

File:

PDF, 1.15 MB

english, 1992

21

Stereospecific synthesis of (+)- and (-)-sesbanimide A

Martin J. Wanner, Nico P. Willard, Gerrit-Jan Koomen, Upendra K. Pandit

Journal:

Year:

1987

Language:

english

File:

PDF, 657 KB

english, 1987

22

Synthesis of acyclic analogues of sesbanimides A and B

Jan C. van den Bos, Wilhelmus J. Vloon, Gerrit-Jan Koomen, Upendra K. Pandit

Journal:

Year:

1991

Language:

english

File:

PDF, 524 KB

english, 1991

23

Ring D modifications of ellipticine. Part 2. Chlorination of ellipticine via its N-oxide and synthesis and selective acetylation of 5,6,11-trimethyl-5H-benzo[b]carbazole.

Adrian T. Boogaard, Upendra K. Pandit, Gerrit-Jan Koomen

Journal:

Year:

1994

Language:

english

File:

PDF, 1.08 MB

english, 1994

24

An approach to novel ellipticine glycosides

Albert Langendoen, Gerrit-Jan Koomen, Upendra K. Pandit

Journal:

Year:

1988

Language:

english

File:

PDF, 475 KB

english, 1988

25

Inter- and intramolecular addition of ester anions to nicotinium salts: A facile approach to nauclefine and ellipticine derivatives

Martin J. Wanner, Gerrit Jan Koomen, Upendra K. Pandit

Journal:

Year:

1983

Language:

english

File:

PDF, 984 KB

english, 1983

26

Stereoselective formation of tetrahydrofurans during allyltrimethylsilane additions to L-xylose derivatives

Ronald A. Veloo, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

1992

Language:

english

File:

PDF, 1.39 MB

english, 1992

27

Biomimetic synthesis of quinolizidine alkaloids

Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

1991

Language:

english

File:

PDF, 928 KB

english, 1991

28

New phosphonium ylides by functionalization of triphenylphosphoranylideneacetamide

Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 282 KB

english, 1992

29

Enantiopure tetrahydroisoquinolines via N-sulfinyl Pictet–Spengler reactions

Christiaan Gremmen, Martin J Wanner, Gerrit-Jan Koomen

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 324 KB

english, 2001

30

The synthesis of new heterocyclic bridged ring systems. Analogs of tetrahydro-β-carbolines

Christiaan Gremmen, Brigitte E.A. Burm, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 329 KB

english, 1998

31

An efficient hetero Diels-Alder approach to imidazo[4,5-c]pyridazines as purine analogues

Paymaneh Y.F. Deghati, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 230 KB

english, 1998

32

Solid phase synthesis of fumitremorgin, verruculogen and tryprostatin analogs based on a cyclization/cleavage strategy

Arnold van Loevezijn, Jan H. van Maarseveen, Karel Stegman, Geb M. Visser, Gerrit-Jan Koomen

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 281 KB

english, 1998

33

Mild and regioselective nitration of 1-deazapurine nucleosides using TBAN/TFAA

Paymaneh Y.F Deghati, Hans Bieräugel, Martin J Wanner, Gerrit-Jan Koomen

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 185 KB

english, 2000

34

Regioselective nitration of purine nucleosides: synthesis of 2-nitroadenosine and 2-nitroinosine

Paymaneh Y.F Deghati, Martin J Wanner, Gerrit-Jan Koomen

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 101 KB

english, 2000

35

Synthesis of enantiomerically pure (S)-(−)-propranolol from sorbitol

Ronald A. Veloo, Gerrit-Jan Koomen

Journal:

Tetrahedron: Asymmetry

Year:

1993

Language:

english

File:

PDF, 199 KB

english, 1993

36

2-Nitro analogues of adenosine and 1-deazaadenosine: synthesis and binding studies at the adenosine A1, A2A and A3 receptor subtypes

Martin J. Wanner, Jacobien K. Von Frijtag Drabbe Künzel, Ad P. IJzerman, Gerrit-Jan Koomen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 139 KB

english, 2000

37

Inhibition of BCRP-mediated drug efflux by fumitremorgin-type indolyl diketopiperazines

Arnold van Loevezijn, John D Allen, Alfred H Schinkel, Gerrit-Jan Koomen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

38

Synthesis of the brominated marine alkaloids (±)-arborescidine A, B and C

Brigitte E.A. Burm, Michaël M. Meijler, Jacco Korver, Martin J. Wanner, Gerrit-Jan Koomen

Journal:

Year:

1998

Language:

english

File:

PDF, 742 KB

english, 1998

39

A new synthesis of temozolomide

Wanner, Martin J., Koomen, Gerrit-Jan

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2002

Language:

english

File:

PDF, 101 KB

english, 2002

40

Inhibition of pig kidney diamine oxidase by nazlinin and nazlinin derivatives

Elisabeth Cheng, Henk L. Dekker, Bob F. van Gelder, Gerrit-Jan Koomen

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1995

Language:

english

File:

PDF, 295 KB

english, 1995

41

Enantiopure Tetrahydro-β-carbolines via Pictet−Spengler Reactions with N -Sulfinyl Tryptamines

Gremmen, Christiaan, Willemse, Bianca, Wanner, Martin J., Koomen, Gerrit-Jan

Journal:

Organic Letters

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

42

Solid phase synthesis of C2,N6-disubstituted adenosine analogues

Rodenko, Boris, Wanner, Martin J., Koomen, Gerrit-Jan

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2002

Language:

english

File:

PDF, 185 KB

english, 2002

43

Oxidative Deamination of Tetrahydroanabasine with o -Quinones: An Easy Entry to Lupinine, Sparteine, and Anabasine

Wanner, Martin J., Koomen, Gerrit-Jan

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 317 KB

english, 1996

44

Stereoselective Synthesis of the Indole Alkaloids Nitrarine, Nitramidine, and Isomers. A Biomimetic Approach

Wanner, Martin J., Koomen, Gerrit-Jan

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 742 KB

english, 1994

45

Palladium-Catalyzed Animation of 6-Chloropurine. Synthesis of N 6 -Substituted Adenosine Analogues

Barends, Judith, der Linden, Johannes B. van, Delft, Floris L. Van, Koomen, Gerrit-Jan

Journal:

Nucleosides and Nucleotides

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

46

Synthesis and Antitumor Activity of Methyltriazene Prodrugs Simultaneously Releasing DNA-Methylating Agents and the Antiresistance Drug O 6 -Benzylguanine

Wanner, Martin J., Koch, Melle, Koomen, Gerrit-Jan

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 140 KB

english, 2004

47

N 6 -Cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a Very Selective Agonist with High Affinity for the Human Adenosine A 1 Receptor

Beukers, Margot W., Wanner, Martin J., Von Frijtag Drabbe Künzel, Jacobien K., Klaasse, Elisabeth C., IJzerman, Adriaan P., Koomen, Gerrit-Jan

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 152 KB

english, 2003

48

Biomimetic Synthesis of Nitraramine

Wanner, Martin J., Koomen, Gerrit-Jan

Journal:

Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 530 KB

english, 1995

49

Potential carcinostatics. 4. Synthesis and biological properties of erythro- and threo-.beta.-fluoroaspartic acid and erythro-.beta.-fluoroasparagine

Wanner, Martinus J., Hageman, Johanna J. M., Koomen, Gerrit Jan, Pandit, Upendra K.

Journal:

Journal of Medicinal Chemistry

Year:

1980

Language:

english

File:

PDF, 398 KB

english, 1980

50

Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors

Ghisaidoobe, Amar T., van den Berg, Richard J. B. H. N., Butt, Saleem S., Strijland, Anneke, Donker-Koopman, Wilma E., Scheij, Saskia, van den Nieuwendijk, Adrianus M. C. H., Koomen, Gerrit-Jan, van L

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 768 KB

english, 2014